Name: Carmel Duffin

Theme: Cytopathology

OPTION LIST

A	15 years	I	Ovarian cancer
B	30-40 years	J	Squamous to glandular epithelium
C	65 years	K
D	CIN1	L
E	CIN2	M
F	CIN3	N
G	Glandular to squamous epithelium	O
H	Invasive cervical cancer	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. The peak incidence of cervical cancer occurs at what age?

2. The metaplasia that occurs in the transformation zone involves which cell-types?

3. A 27 year old woman undergoes a routine Pap test. Histology shows increased squamous epithelium with atypical cells with increased nuclear to cytoplasmic ratio and hyperchromatic nuclei present in the lower 1/3 of the epithelial layer from the basement membrane.

4. Histology from the transformation zone in a 40 year old woman demonstrates increased squamous cells with abnormal features through the full thickness of the epithelium. The basement membrane has been breached.

5. NHS Cervial Screening Programme currently screens women with normal Pap tests up to what age?

ANSWERS

1. B

2. G

3. D

4. H

5. C